Browsing by Author "Chirigos, M. A."
Now showing items 1-11 of 11
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Cytotoxic activity of interferon-treated macrophages studied by various inhibitors
Schultz, R. M.; Pavlidis, Nicholas; Stylos, W. A.; Chirigos, M. A. (1978)The ability of interferon-treated macrophages to kill or inhibit the growth of tumor cells is markedly influenced by the local environment. The macrophage cytotoxic effector system is regulated by serum and other environmental ...
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Article
Effect of maleic anhydride-divinyl ether copolymers on experimental M109 metastases and macrophage tumoricidal function
Pavlidis, Nicholas; Schultz, R. M.; Chirigos, M. A.; Luetzeler, J. (1978)Pyran copolymer (NSC-46015) was compared with five maleic anhydride-divinyl ether copolymers (MVEs) of narrow molecular weight range both for the ability to render macrophages nonspecifically tumoricidal and to retard the ...
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Article
Effects of adriamycin and cyclophosphamide treatment on induction of macrophage cytotoxic function in mice
Stoychkov, J. N.; Schultz, R. M.; Chirigos, M. A.; Pavlidis, Nicholas; Goldin, A. (1979)The effects of i.p. and s.c. Adriamycin and cyclophosphamide treatment of BALB/c x DBA/2F1 mice were studied alone and in combination with immunotherapeutic agents, pyran copolymer and Bacillus Calmette-Guérin, on macrophage ...
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Effects of whole body X-irradiation and cyclophosphamide treatment on induction of macrophage tumoricidal function in mice
Schultz, R. M.; Pavlidis, Nicholas; Chirigos, M. A.; Weiss, J. F. (1978)
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Article
Factors affecting macrophage cytotoxic activity with particular emphasis on corticosteroids and acute stress
Schultz, R. M.; Chirigos, M. A.; Stoychkov, J. N.; Pavlidis, Nicholas (1979)
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Macrophage activation and antitumor activity of a Brucella abortus ether extract, Bru-Pel
Schultz, R. M.; Chirigos, M. A.; Pavlidis, Nicholas; Youngner, J. S. (1978)Bru-Pel and Brucella abortus lipopolysaccharide (LPS) were tested for both macrophage activation and antitumor activity in an artificial metastasis model. Resting macrophages were rendered nonspecifically tumoricidal for ...
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Macrophage involvement in the antitumor activity of Brucella abortus ether extract against experimental lung carcinoma metastases
Schultz, R. M.; Pavlidis, Nicholas; Chirigos, M. A. (1978)
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Prevention of macrophage tumoricidal activity by agents known to increase cellular cyclic AMP
Schultz, R. M.; Pavlidis, Nicholas; Stoychkov, J. N.; Chirigos, M. A. (1979)
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Article
Regulation of macrophage tumoricidal function: a role for prostaglandins of the E series
Schultz, R. M.; Pavlidis, Nicholas; Stylos, W. A.; Chirigos, M. A. (1978)Exogenously added prostaglandins E1 and E2, but not F2alpha, inhibited the tumoricidal activity of interferon-activated macrophages of mice. A role for adenosine 3',5'-monophosphate (cyclic AMP) in modulating macrophage ...
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Role of E-type prostaglandins in the regulation of interferon-treated macrophage cytotoxic activity
Schultz, R. M.; Stoychkov, J. N.; Pavlidis, Nicholas; Chirigos, M. A.; Olkowski, Z. L. (1979)
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Article
Stress-induced impairment of macrophage tumoricidal function
Pavlidis, Nicholas; Chirigos, M. A. (1980)Several studies have shown the effect of stress on immune cells and their functions. The purpose of the present work was to investigate the influence of acute immobilization stress on macrophage nonspecific tumoricidal ...